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OXALIC ACID

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Properties of Oxalic acid – C2H2O4

C2H2O4Oxalic acid
Molecular Weight/ Molar Mass90.03 g/mol
Density1.90 g cm−3
AppearsWhite crystals
Melting Point189 to 191 °C

C2H2O4 Uses (Oxalic acid)

        • It is used in the dyeing process as a mordant
        • It is used in removing rust
        • In lanthanide chemistry, it is used as an important reagent
        • It is applied on marble sculptures to make it shine
        • It is used in the manufacture of dye
        • It is used in bleaches
        • It is used in removing food and ink stains
        • It is used in developing photographic film
        • It is used in wastewater treatment to remove the calcium deposit.

Oxalic acid’s conjugate base is the hydrogen oxalate anion and its conjugate base (commonly known as oxalate) is a competitive lactate dehydrogenase (often abbreviated to LDH) enzyme inhibitor. LDH catalyses the conversion of pyruvate to lactic acid (end product of the fermentation, which is an anaerobic process) oxidizing coenzyme NADH to NAD+ and H+ at the same time. Restoring NAD+ levels is necessary if anaerobic energy metabolism is to continue through glycolysis. Because cancer cells preferentially use anaerobic metabolism, LDH inhibition has been shown to inhibit tumour development and growth. Thus, this compound provides an interesting possible course for the treatment of certain cancers.

Health Hazard

Oxalic acid is a strong poison. The toxic symptoms from ingestion include vomiting, diarrhoea, and severe gastrointestinal disorder, renal damage, shock, convulsions, and coma. Death may result from cardiovascular collapse. Oxalic acid is an irritant of the eyes, mucous membranes, and skin. Inhalation or ingestion may result in kidney damage.

Oxalic acid is a strong poison. The toxic symptoms include renal damage, shock, convulsions. The toxicity arises as oxalic acid reacts with the calcium in the tissues to form calcium oxalate, thereby upsetting the calcium potassium ratio. The deposition of oxalates in the kidneys tubules may result in kidney damage.

Oxalic acid poisoning can result in headaches, dizziness, nausea, vomiting, convulsions, coma, and even death. A skin rash, discomfort, redness, blisters, and slow-healing ulcers can result from prolonged or recurrent exposure.



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